The Edward Jones Dome will play rare host to Monday Night Football when the St. Louis Rams host NFC West division rival San Francisco at 8:30 PM ET. A weighty 75% of the expert NFL predictions are on San Francisco on the 49ers vs Rams Betting Odds. The 49ers (3-2 SU 3-2 ATS) are coming off consecutive wins over potential playoff contenders Philadelphia and Kansas City despite a lockeroom rumblings that head coach Jim Harbaugh is about to get canned. The Rams (1-3 SU 1-3 ATS) have been hammered by injuries but have played with heart under head coach Jeff Fischer. Can the Rams unravel a supposedly fragile 49ers team that is on the brink of destruction? Our handicappers give away our expert NFL predictions.
49ers vs Rams Betting Odds Moneyline have St. Louis +160 (Bet $500 to win $800) at SPORTS BETTING ONLINE
Expert NFL Predictions Analysis: Jim Harbaugh might be getting run out of town by the teams owner but the 49ers talent on the playing field is in a different class than the Rams. St. Louis takes on a personality similar to their pilot Jeff Fischer; blue-collar, lunch-pail types that overachieve. San Francisco is similar in approach to St. Louis but only they have big play difference makers on both sides of the ball. San Francisco is built on a ground and pound philosophy and in what figures to be a physical game their bigger horses should outclass the Rams smaller ponies. 49ers vs Rams Betting Odds Total is at 43.5 points
Key injuries to take note of from the 49ers are TE Vernon Davis (2.0 points spread) and LT Anthony Davis (1.0 point spread). The Rams notable injury is RB Zac Stacy (1.0 point spread). In a game that is sure to feature the ground game the 49ers with old trail horse Frank Gore should bull their way to a cover against the spread.
Expert NFL Predictions Play: San Fran -3.5 at SPORTS BETTING ONLINE
49ers vs Rams Tale-Of-The-Tape
RB: B/B (STL C without Z. Stacy)
WR: A/C (San Fran B without V. Davis)
OL: B/C (San Fran C without A. Davis)
Home-Field: St. Louis +3.5
Intangibles: St. Louis +0.5
ESPN2 News Actual Spread: San Francisco -5